Understanding In Vivo Chromatic Aberrations in Pseudophakic Eyes Using on Bench and Computational Approaches

Diffractive multifocal intraocular lenses (IOLs) modulate chromatic aberration and reduce it at certain distances due to interactions between the refractive diffractive components. However, extent which computer modeling on bench measurements of IOL translate in patients implanted with these IOLs (MIOLs) is not yet fully understood. In this study, we compare difference focus longitudinal aberrations pseudophakic different designs (monofocal trifocal IOLs) materials (hydrophobic hydrophilic), compared them predictions from eye models same IOLs. Patient data consisted results 63 eyes reported four studies obtained psychophysically visual testing channel a custom-developed polychromatic adaptive optics system. Computational were using ray tracing models, modulation transfer function (MTF) physical models. We found that LCA (in vivo/simulated) for far vision was 1.37 ± 0.08 D/1.19 D monofocal hydrophobic, 1.21 D/0.88 hydrophilic, 0.99 0.06 MIOL 0.82 0.05 hydrophilic. For intermediate near vision, 0.67 0.10 D/0.75 0.23 D/0.19 hydrophobic 0.27 0.15 D/0.38 D/−0.13 respectively. conclusion, computational allowed evaluating vivo lenses.